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Article Colon and Rectal Cancer Risk Associated with Obesity Dr. Ohan Karatoprak, MD As I talked and wrote about the relationship between excessive body fat and certain cancers in the MDFatLoss online seminars and Success Guide, here is the results of a research study about colon and rectal cancer risk associated with obesity. A research project conducted by Dr. Susanna Larsson and Alicja Wolk, from the Division of Nutritional Epidemiology, Karolinska Institutet, Stockholm, Sweden, that conducted an independent review of a number of research studies regarding the relationship between obesity and cancer. After reviewing 30 studies of Body Mass Index (BMI), the conclusion was that increased BMI was associated with increased risk of colon cancer in both men and women. But the association was stronger in men. BMI was positively associated with rectal cancer in men, but not in women. Also, colon cancer risk increased with increasing waist circumference (per 10 centimeter increase) in both men and women and with increasing waist-hip-ratio (per 0.1 unit increase) in both men and women. The researchers noted that colorectal cancer is the third most common cancer worldwide, with the highest rates observed in North America, Australia, and Western Europe. So obesity plays a significant role in colorectal cancer development. Also, related metabolic abnormalities, such as insulin resistance and hyperinsulinemia may be responsible for the associations with colorectal cancer risk and for the high incidence of this cancer in industrialized countries. Please refer to the MDFatLoss seminars and Success Guide for more information about the relationship between obesity and cancer, and ways to reduce your risk. Join www.MDFatLoss.com and learn about overcoming insulin resistance, obesity, and cancer prevention.
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